Elevated sister chromatid exchange frequencies in New Zealand Vietnam War veterans.

Prepared by Louise Edwards Institute of Molecular BioSciences Massey University

From July 1965 until November 1971, New Zealand Defence Force Personnel fought in the Vietnam War. During this time the United States military forces sprayed more than 76,500,000 litres of phenoxylic herbicides over parts of Southern Vietnam and Laos. The most common herbicide sprayed was known as ‘Agent Orange’. All of the Agent Orange sprayed during the Vietnam War was contaminated with 2,3,7...

Sister chromatid exchange analysis in some Holstein bulls

Chromosomal appearance of 12 Holstein bulls selected for artificial inseminations were examined bysister chromatid exchanges (SCEs). For differential staining of sister chromatids bromodeoxyuridine (BrdU)was inoculated in lymphocyte cultures. The mean, maximum and minimum number of SCE per cell weredetermined 6.8 ± 1.14, 8.3 ± 1.1 and 5.7 ± 1.5, respectively. SCE frequencies of all animals were...

The mortality and cancer experience of New Zealand Vietnam war veterans: a cohort study

OBJECTIVES The aim was to observe the patterns of mortality and cancer incidence in New Zealand Vietnam veterans. The objectives were to assess whether the patterns of disease observed were consistent with those associated with military service in Vietnam, and similar to the patterns identified in other groups of Vietnam veterans. DESIGN A historical cohort study. SETTING Veterans, identifi...

The influence of culture media on chromosome aberration levels, sister chromatid exchange frequencies, and the rate of cell proliferation: comparison of Iscove's low folate medium with Eagle's MEM.

Study of the Effect of MMC on the Sister Chromatid Exchange in the Human Lymphocytes

Some environmental mutagenic agents cause genomic instability and increase susceptibility of DNA damage. One of them is mitomycin C which is connected to DNA as an alkylating factor and affects susceptible cells to reduction reactions. This drug is used in chemotherapy and treatment of tumors. Study of genomic instability in the presence of different concentrations of MMC can show susceptibilit...